The
following questions have one or more correct answers. Use the notations given
below:
A:
Only answer 1 is correct
B:
Only answer 3 is correct
C:
Only answers 1 and 5 are correct
D:
Only answers 2 and 3 are correct
E:
Only answers 2 and 4 are correct
72.
Choose the drugs which contain alkaloids derived from ornithine.
1)
Hellebori rhizome 2)
Henbane leaf 3) Cocae
leaf
4)
Ribes nigri leaf 5)
Valeriana rhyzome
73.
Which statements are correct concerning with proazulens?
1)
Proazulens show orange spot on TLC by spraying with cc. ammonium hydroxyde.
2)
Proazulens give blue colour with EP reagent on heating.
3)
Proazulens give red colour on ninhydrine reagent.
4)
The proazulens transform into chamazulene by heating with mineral acid.
5)
The proazulens give yellow precipitate with resorcinole.
74.
The following properties are characteristic for saponins:
1)
They give precipitate by shaking with water. 2) They are diterpenes.
3)
They cause haemolysis on erythrocytes. 4) They give negative
Keller-Kiliani test.
5)
They have usually acetic acid in their molecules.
75.
Which of the following properties are characteristic for tannins?
1)
They give precipitate on alkaloids.
2)
They give yellow or bluish-red color on iron-III-chloride.
3)
They are 3-phenylbenzopyrane-derivatives. 4) They give pale pink precipitate on
iodine.
5)
They transform the hide into leather.
76.
Choose the antraquinone containing drugs.
1)
Betulae folium
2) Graminis rhizome 3) Rhei rhizome
4)
Herniariae herba
5) Rubi ideae folium
77.
Galenicals prepared from Cinchona bark are used as .............. .
1)
abortive 2) bitter tonic 3) stomachic 4) cough reliever 5) emetic
78.
Pilocarpin the alkaloid of Jaborandi folium has.................... .
1)
antagonist effect of atropine
2) agonist effect of atropine 3) sedative effect
4)
diuretic activity
5) emetic activity
79.
Which of the following compounds are C-glycosides:
1)
arbutin. 2) vitexin. 3) gentiopicrine. 4) aloin. 5) hypericine.
80.
Choose the drugs containing purine derivatives.
1)
Capsicum fuictus 2) Pasta guarana 3) Colae semen 4) Podophylum 5) Pyrethri flos
81.
Choose the alkaloids derived from tryptophan.
1)
ephedrine 2) chinin 3) vinchrystin 4) tomatidenol 5) protoveratrin A
82.
The alkaloids of Ipecacuanha root have.....................effect.
1)
expectorant 2) pain killer 3) sedative 4) antipyretic 5) amoebicide
83.
Opium is used in the medicine as............................... .
1)
tranquillant 2)
starting material for morphine production
3)
pain killer 4)
laxative 5)
emetic
84.
In the typical alkaloids N atom(s) derived from amino acid is/are present:
1)
in heterocyclic ring 2)
as ammonium cation 3) as
substituent of benzene ring
4)
as substituent of pyrane ring
5) in their side chain
85.
Choose the plant species which are steroid sources for Industry.
1)
Licorice species 2)
Dioscorea composite
3) Smilax regelii
4)
Ipomea purge 5)
Hydrastis canadensis
86.
Which are the most frequently occurring special sugars present in the
cardioactive glycosides?
1)
cymarose 2) apiose 3) xylose 4) fucose 5) digitoxose
87.
Choose the drugs which contain no cardioactive compounds.
1)
Thornapple leaf 2)
Lily of the valley shoot
3) Oleandri folium
4)
Foxglove leaf 5)
Allii bulb
88.
The presence of alkaloid in plant material can be tested by the following
reagents:
1)
3,-dinitrobenzoic acid in NaOH (Kedde reagent).
2)
Potassium-mercury iodide solution (Mayer reagent). 3) 2,4-dinitrophenylhydrazin solution.
4)
potassium bismuth iodine solution (Dragendorff reagent). 5) aluminium trichloride in alcohol.
89.
The alkaloids are grouped by the origin and position of nitrogen atom(s) as
proto-,
typical,
and pseudo-alkaloids respectively. Choose the pseudo-alkaloids from the followings:
1)
protoveratrine B. 2) pilocarpine. 3) thebaine. 4) ergocornin. 5) capsaicine.
90.
Which statements are characteristic for the pentacyclic triterpenes from the
followings:
1)
They were formed of farnezyl-pyrophosphate.
2)
In their structure(s) can be found usually unit(s) derived from loganine.
3)
At the carbon atom number 3 of the base structure has rarely oxo and hydroxyl groups
respectively.
4)
They have usually low melting point.
5)
The pentacyclic triterpenes frequently occur in glycosidic and esther form as
well.
91.
The alkaloids are present in plants in the form of........................ .
1)
mineral salt
2) free basis 3) salt of
organic acid
4)
lactones of organic acid 5)
esther of mineral acid
92.
Choose the alkaloids derived from phenylalanine.
1)
tubocurarine 2) toxiferin C 3) theophyllin 4) chinidine 5) narcotine
93.
Which ones are correct from the following statements concerning with Opium?
1)
Opium is the dried latex obtained by incision from unripe capsule of Opium
poppy.
2)
Opium is the dried juice of the cutting leaves of Opium poppy.
3)
Opium is the dried water extract of the shoot of Opium poppy.
4)
Opium with good quality has 1.5 % morphine content.
5)
Opium is used in the medicine as diuretics and laxative.
94.
Choose the right assay for determination of alkaloid content of drugs.
1)
azeotropic distillation
2) photometry (in UV and visible light) 3) gravimetry
4)
titration in non-aqueous media 5) titration according to Volchard’s
method
95.
Choose of the following compounds which the Opium contains.
1)
chelidonin 2) narceine 3) hypericine 4) narcotine 5) heroin
96.
Which are of the following drugs having high ascorbic acid content?
1)
Hippopheae fruit 2) Manna 3) Agar 4) Galliae odorati herba 5) Rosa hips
97.
Which properties are characteristic for the starches?
1)
They can be dissolved in cold water very well. 2) Starches form a jelly on boiling
water.
3)
Starches give blue or green product on mineral acids.
4)
The starches turn the plane of the light polarization.
5)
Starches contain amino acids in a large amount.
98.
How to protect the drugs against the undesirable postmortal changing?
1)
Dry the plant material so quickly as soon as possible.
2)
Moistened the plant material with a calculated amount of water and keep it in a
refrigerator.
3)
The plants are stored at a cold place in covered container.
4)
Put the plant material in a hermetically sealed container and kept it at room
temperature.
5)
Stored the plant material in deep freezer at -18 oC.
99.
Which is the right reagent for identification of Ergot alkaloids?
1)
van Urk 2) Fehling I and II 3) iron-III-chloride
4)
phloroglucinol in hydrochloric acid
5) EP test
100.
Choose the type of chemical structure of loganin.
1)
iridoid 2) labdan type diterpene 3) pseudoguaianolid 4) abietane 5) clerodan
101.
What kind of type of compounds can be detected by Mayer’s reagent?
1)
sesterterpenes 2) starches 3) alkaloids 4) procyanidines 5) leucoanthocyanidins
102.
What are iridoids?
1)
Stress compounds characteristic for Lamiaceae family. 2) Sesterterpenes with acrid taste.
3)
The iridoids are monoterpenes with cyclopentan-(c)-pyrane structure.
4)
Pseudoalkaloids. 5) Iridoids
are constituent of balms since they have a pleasant scent.
103.
The senna-emodin aglycones and senna-emodin glycosides are
....................derivatives.
1)
tetraterpenes 2)
monoterpenes with labdane structure
3) anthraquinones
4)
pseudoguaianolides 5) iridoids
104.
Which are the right reagents for the detection of cardioactive glycosides?
1)
Baljet reagent 2)
Hirschson reagent 3)
Benzidine in alcohol
4)
Froehde reagent 5) Kedde
reagent
105.
..........................can be detected by Keller-Kiliani test.
1)
The aglycon of digitalis glycosides 2) The digitoxose of
digitalis glycosides
3)
The cymarose from the strophanthus glycosides 4) Strophantidine 5) Digitoxigenin
106.
Choose the plants which become valuable by fermentation.
1)
Calami rhizome 2) Gentian root and rhizome 3) Ratanhia root 4) Theae leaf
5) Lime flower
107.
Choose the drugs which can quantify by photometry.
1)
Gentian root 2) Cinchona bark 3) Alder Buckthorn 4) Nettle root 5) Coriandri fructus
108.
Iridoids are highly oxygenated monoterpenes. They were named
.............................
1)
after their black degradation products.
2) after
their blue color in acidic media.
3)
after an ant species Iridomirmex humilis since this type of
compounds had been isolated from them.
4)
after their pleasant odor (fragrance) similar to Iris germanica.
5)
after an Irish scientists who discovered this type of component.
109.
The bitter value shows the ........... of an extract made of 1g drug which has
just bitter taste.
1)
largest dilution
2) lowest dilution 3) smallest
concentration
4)
largest concentration 5)
highest trituration
110.
Choose the volatile oils having higher density than the water.
1)
Aetheroleum menthae piperitae
2) Aetheroleum cinnamomi
3)
Aetheroleum synapis synthetic 4)
Aetheroleum rosae 5)
Aetheroleum rosemarini
111.
Choose the right reagent for identify of Ipecacuanha root.
1)
EP reagent 2)
Froehde reagent 3)
0.01N iodine in alcoholic solution
4)
chlorogen with diluted hydrochloric acid 5) Behrens reagent
112.
Choose the active compounds of Hops.
1)
humulon 2) cnicine 3) loganin 4) picrosalvine 5) lupulon
113.
Choose the homopolysaccharide containing drugs.
1)
Acacia gum 2) Cotton 3) Potato starch 4) Agar 5) Marsmallow leaf and root
114.
Choose of the following volatile oils having higher density than the water.
1)
Aetheroleum thyme 2)
Aetheroleum caryophylli 3)
Aetheroleum lavandulae
4)
Aetheroleum cinnamomi
5) Aetheroleum pini pumilionis
115.
Which of the following alkaloid bases are liquids?
1)
morphine 2) nicotine 3) arecoline 4) scopolamine 5) chinine
116.
Select the compounds which are terpenoids!
1)
iridoids 2) anthocyanins 3) mucilages 4) tannins 5) carotenoids
117.
Which of the following alkaloids are bisindols, characteristic in Catharanthi
herba?
1)
vincamine 2) vincristine 3) vinblastine 4) catharanthine 5) vindoline
118.
Which of the following saccharides are dideoxy hexoses, characteristic in
cardiac glycosides?
1)
xilose 2) diginose 3) galactose 4) digitoxose 5) glucose
119.
Select the vegetable drugs containing pseudoalkaloids!
1)
Chinae succirubrae cortex
2) Veratri rhizome 3) Solani herba
4)
Secale cornutum 5)
Ephedrae herba
120.
Which of the following vegetable drugs contain sesquiterpene-γ-lactones as
bitter
compounds?
1)
Absinthii herba
2) Centaurii herba 3) Marrubii herba
4)
Gentianae radix
5) Cardui benedicti herba
121.
Select the vegetable drugs containing monoterpene bitter compounds!
1)
Absinthii herba
2) Centaurii herba 3) Marrubii
herba
4)
Gentianae radix
5) Cardui benedicti herba
122.
Which of the following vegetable drugs contain proazulenogenes?
1)
Chamomillae anthodium 2)
Coriandri fructus 3)
Menthae piperitae folium
4)
Melissae folium
5) Cardui benedicti herba
123.
Select those essential oils which contain phenylpropanoids!
1)
Aetheroleum coriandri 2)
Aetheroleum foeniculi 3)
Aetheroleum lavandulae
4)
Aetheroleum cinnamomi 5)
Aetheroleum chamomillae
124.
Which of the following compounds are C-glycosides?
1)
aloin 2) rutin 3) hyperoside (Hyperin) 4) lanatoside-C 5) vitexin
125.Which
of the following vegetable drugs contain galactans (polysaccharides of the galactose).
1)
Lana gossypii 2) Agar-agar 3)
Cichorii radix 4) Carrageen 5) Gummi arabicum
126.
Select the vegetable drugs with significant silicon content.
1)
Verbasci flos 2) Pulmonariae herba 3) Equiseti herba 4) Lamii folium 5) Tiliae flos
127.
Which of the following reactions are specific for alkaloids?
1)
Vitali-reaction 2)
Borntrager-reaction
3) Kedde-reaction
4)
Liebermann-Burchard-reaction 5)
Marquis-reaction
128.
Which of the following reactions are specific for cardiac glycosides?
1)
Kedde-reaction 2)
Murexid-reaction 3)
Borntrager-reaction
4)
Vitali-reaction
5) Legal-test
129.
Which of the following reactions are specific linked to the presence of the
α,β-unsaturated-γ-lactone?
1)
Liebermann-Burchard reaction 2)
Kedde-reaction 3)
Keller-Kiliani-reaction
4)
Legal test 5)
Xanthidrol-reaction
130.
Select the lysine-derived alkaloids from the following list!
1)
coniine 2)
pilocarpine
3) strychnine
4)
tropine 5)
pseudopelletierine
131.
Select the tryptophan-derived alkaloids from the following list!
1)
atropine 2) quinine 3) fcgonine 4) strychnine 5) quinolizidine
132.
Which of the following alkaloid-drugs play a significant world-wide role in
pharmaceutical
industry?
1)
Scopoliae herba 2)
Catharanthi herba 3)
Secale cornutum
4)
Vincae minoris herba 5)
Chelidonii herba
133.
Which of the following vegetable drugs contain cardenolide-glycosides?
1)
Crataegi summitas 2)
Hellebori rhizome 3)
Convallariae herba
4)
Crataegi fructus 5)
Scillae bulbus
134.
Which of the following vegetable drugs contain bufadienolide-glycosides?
1)
Scillae bulbus 2)
Convallariae herba 3)
Digitalis lanatae folium
4)
Oleandri folium 5)
Hellebori rhizoma et radix
135.
Which of the following alkaloids are quaternary?
1)
berberine 2) bhelidonine 3) vincamine 4) brucine 5) C-toxiferine
136.
Select the vegetable drugs with significant rutin (rutoside) content!
1)
Fagopyri herba
2) Liquiritiae radix
3) Hyperici herba
4)
Aurantii pericarpium 5)
Sophorae japonicae flos
137.
Which of the following natural compounds are non-steroid antiinflammatory
agents?
1)
azulene 2) arbutin 3) scopoletin 4) primulic acid 5) aescin (escin)
138.What
type of compounds are formed through acid catalysed decomposition of procyanidins?
1)
flavanone 2) catechin 3) flavonol 4) anthocyanidine 5) chalkone
139.
Which of the followings are characteristic for the alkaloid extractor official
in
Pharmacopoeia
Hungarica Editio VII.?
1)
Both solid/liquid and liquid/liquid extraction take place.
2)
Extraction takes place at high temperature.
3)
It works with organic solvent heavier than water.
4)
It works with organic solvent either heavier or lighter than water.
5)
It utilizes the differences in solubility of alkaloid bases and their salts in
organic and
wateric phases respectively.
140.
Which of the following natural substances serve as starting material in the semisynthesis
of pregnenolone acetate?
1)
oleanolic acid 2) diosgenin 3) lanatozide-C 4) phytosterols 5) jervine
141.
Which of the following methods are not suitable for the detection of matricin
in
Chamomillae
anthodium?
1)
Extraction followed by UV spectroscopy. 2) High pressure liquid
chromatography.
3)
IR spectroscopy. 4)
Extraction . chromatography. 5)
Specific test - tube test.
142.
Select those vegetable drugs which contain fructosanes!
1)
Cichoriae radix
2) Salep tuber 3) Althaeae
radix
4) Saponariae albae radix 5) Graminis rhizoma
143.
Which of the following medicinal plants are important for pharmaceutical
industry?
1)
Equisetum arvense
2) Catharanthus roseus 3) Salvia
officinalis
4)
Papaver somniferum 5)
Digitalis purpurea
144.
Which of the following vegetable drugs are important for pharmaceutical
industry?
1)
Digitalis lanatae folium 2)
Digitalis purpureae folium
3) Tiliae flos
4)
Rutae herba
5) Sophorae japonicae flos
145.
Which of the following vegetable drugs are official in the Hungarian
Pharmacopoeia
Editio
VII.?
1)
Secale cornutum
2) Belladonnae folium
3) Melissae folium
4)
Digitalis lanatae folium 5)
Digitalis purpureae folium
146.
Which of the following vegetable drugs are not official in the Hungarian Pharmacopoeia
Editio VII.?
1)
Crataegi summitas
2) Catharanthi herba
3) Digitalis lanatae folium
4)
Ratanhiae radix
5) Primulae radix
147.
Select those vegetable drugs which are used as amara aromatics!
1)
Absinthii herba
2) Gentianae radix 3) Tiliae flos
4)
Cynarae folium
5) Calami rhizoma
148.
Marshmallow root and deadly nightshade root can be distinguished by microscopy
on
the
base of:
1)
the form of Calcium oxalate crystals.
2)
the position and arrangement of Calcium oxalate crystals.
3)
the absence or presence of scleroids.
4)
the absence or presence of Calcium oxalate crystals.
5)
the absence or presence of bands of fibres.
149.
Which of the following vegetable drugs contain active compounds used in cardiac
insufficiency?
1)
Rauwolfiae radix 2)
Crataegi summitas 3) Convallariae herba
4)
Chinae cortex 5)
Vincae minoris herba
150.
Select those vegetable drugs which contain laxative agents!
1)
Sennae fructus
2) Hyperici herba
3) Urticae radix
4)
Equiseti herba
5) Agrimoniae herba
151.
Which of the following vegetable drugs contain indole alkaloids?
1)
Veratri rhizome
2) Colchici semen 3) Catharanthi
herba
4)
Chinae succirubrae cortex 5)
Arecae semen
152.
Select those vegetable drugs which have sulphur containing active ingredients!
1)
Echinaceae radix 2)
Tropeoli herba
3) Ginseng radix
4)
Allii sativi bulbus
5) Urticae radix
153.
Which of the following vegetable drugs have significant vitamin content?
1)
Hippopheae pseudofructus et semen 2)
Hippocastani semen
3)
Sinapis albae semen 4)
Centaurii herba 5)
Cynosbati pseudofructus
154.Conii
fructus can be distinguished from Anisi vulgaris fructus by microscopy on the base
of:
1)
Conii fructus has secretion (essential oil) ducts. 2) there are no trichomes on Conii
fructus.
3)
Anisi vulgaris fructus has no secretion (essential oil) ducts.
4)
Conii fructus has no secretion (essential oil) ducts. 5) non of them contain
aleurones.
155.
Which of the following vegetable drugs contain carvone in the essential oil?
1)
Menthae crispae folium
2) Anisi vulgaris fructus 3) Coriandri fructus
4)
Menthae piperitae folium
5) Carvi fructus
156.
Select the vegetable drugs with significant carotinoide content!
1)
Capsici fructus
2) Papaveris rhoeados flos 3) Cyani flos
4)
Malvae flos 5)
Hippopheae pseudofructus
157.
Which of the following reactions serve as possibilities in the detection of
quinoline alkaloids?
1)
Vitali reaction 2)
Thalleiochin reaction 3)
Murexid reaction
4)
Vogel reaction
5) Keller-Kiliani reaction
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