1.
The volatile oils are the complex mixture of…….
A)
mono- and sesquiterpenes as well as phenyl-propane derivatives.
B)
mono- and diterpene alcohols and ethers.
C) sesquiterpenes and other aromatic compounds.
D)
monoterpene acids and lactones.
E) monoterpene ethers and aldehydes.
2.
Sesquiterpenes are formed of............in the plants.
A)
farnezyl-pyrophosphate
B) stress compounds
C) colouring material
D)
degraded products of triterpenes E)
pathological products
3.
What are known as balsams?
A)
resins dissolved in volatile oil B) a mixture of volatile
oils with sesquiterpenes
C)
resins dissolved in water D) polysaccharide
mixed with volatile oil
E)
juice evaporated to dryness
4.
Saponin containing drugs are used as...........
A)
laxative. B) bitter tonic. C) expectorant. D) emetic. E) pain killer.
5.
Alkaloids are naturally occurring compounds which contain .............in their
molecules.
A)
one or more N atom(s) B) two
heterocyclic rings C) one C15
side chain on the benzene ring D) one or more N atom(s) originated from amino
acids
E)
one or more O atoms besides the S atoms
6.
How to extract the alkaloids in mineral salt form from plant?
A)
Heating with organic solvent. B) Boiling with
ammonium-hydroxide and water.
C)
Shaking with water containing mineral acid.
D) Boiling with water and lead acetate.
E)
Warming with mineral acid in organic solvent.
7.
The volatile oils consist of a mixture of.........
A)
oxygen free mono- and diterpenes. B) aliphatic and cyclic
mono- and triterpenes.
C)
aliphatic and cyclic mono- and sesquiterpenes and phenyl-propane derivatives.
D)
highly oxygenated mono- and diterpenes. E) oxygen free di- and monoterpenes.
8.
The iridoids are:
A)
constituents of volatile oils. B) starting unit of the
tannin biogenesis.
C)
precursor of biosynthesis of saponins.
D) precursors of the biogenesis of certain alkaloids.
E)
constituents of fixed oils.
9.
What do you do for getting alkaloids in basis form from the plant material?
A)
Adding some ammonium-hydroxide and water to the pulverised drug.
B)
Making an extract by mineral acid and organic solvent.
C)
Making an extract with some basis and organic solvent.
D)
Adding to the powdered drug some mineral acid and water.
E)
Making an extract with organic solvent and warm it.
10.
Morphin is separable from its side alkaloids because:
A)
morphine has a piperidine ring.
B) morphine has two methoxy groups.
C)
morphine has phenolic hydroxyl group while the side alkaloids have none.
D)
morphine has no phenolic hydroxyl group while the side alkaloid has it.
E)
morphine and its side alkaloids are inseparable.
11.
Which is the right reagent for the detection of rancidity?
A)
concentrated nitric acid B)
phloroglucinol dissolved in diluted HCl
C)
antimony-III-chloride D)
concentrated sulphuric acid
E)
phloroglucinol dissolved in ether and concentrated HCl
12.
Choose the right skeleton for Cinchona alkaloids.
A)
cevan B) tropane C) isoquinoline D) rubanol E) dammarane
13.
Choose the right reagent for alkaloids.
A)
2,4-dinitrophenylhydrazine B)
iron-III-chloride C)
antimony-III-chloride
D)
potassium-tetraiodomercurate E)
phloroglucinol in concentrated hydrochloric acid
14.
How could be prepared a mucilage extract starting from Linseed?
A)
After grinding some water is added to the seed and warm it.
B)
The seed is covered with water without grinding and warming.
C)
After grinding some alcohol is added to the seed.
D)
Without grinding some alcohol is added to the seed.
E)
After grinding it is covered with water without warming.
15.
Ergot is the......................of the fungus Claviceps purpurea.
A)
vegetative form B) dried sclerotium C) ascospore
D) conidiospore E) philamentous hyphae
16.
What is the difference between the chemical structure of cotton and starch?
A)
Cotton consists of lines α-glucose molecules while the starch has branched β-glucose
residue.
B)
Cotton consists of unbranched β-glucose molecules the starch has also
unbranched α- and β-glucose molecules.
C)
Cotton is built up of glucose residues united by 1,4-β-D-glucose links, starch
has
branched
and linear chains of 1,4-α-,and 1,6-α-D-glucose residue.
D)
Both consist of branched and linear 1,2-β-D-glucose residues.
17.
The haemolytic index shows:
A)
the di- and sesquiterpene content of the volatile oils.. B) the saponin content
of the drugs.
C)
the steroid content of the drugs.
D) the aliphatic monoterpene content of the drugs.
E)
the tannin content of the drugs.
18.
Which is the right structure for the flavonoids of Silybum marianum?
A)
dimer flavan-3,4-diol B) monomer
flavon-3-ol C) flavanolignan
D)
simple flavanonol-glycoside E)
isoflavanon-diglycoside
19.
Cocaine is used as...................in the officinal medicine.
A)
narcotic B) emetic C) sedative D) local anaesthetic E) cough suppressant
20.
Choose the right test for identification of anthraquinones.
A)
Marquis test B) Froehde
test C)
Liebermann-Burchard test
D)
Borntraeger test E)
Murexid test
21.
How to detect the procyanidins?
A)
On heating with diluted NaOH procyanidines show green colour.
B)
Procyanidins give yellow colour on concentrated nitric acid.
C)
On heating with a mixture of cc. HCl and N BuOH procyanidines show red colour.
D)
On heating with resorcinol procyanidins give bluish violet colour.
E)
Procyanidins give orange precipitate on Kedde reagent.
22.
The anthraquinone content of the drugs tested by ............................
A)
warming with glacial acetic acid giving red precipitate.
B)
shaking the extract made by organic solvent with diluted ammonium-hydroxide the
water
phase gives red or orange colour.
C)
extracting with water and precipitate with lead acetate showing blue colour.
D)
making a water extract which shows green colour on sulphuric acid.
E)
making organic solvent extract which shows yellow precipitate on heating with dil.
HCl and
chlorine.
23.
What is the right method for making assay for volatile oil content of drugs?
A)
water-damp distillation B) extraction
of light petrol C) distillation by
Marcusson’s
method
D)
determination of loss on drying E)
determination of alcohol extract
24.
Which is the right test for the cardioactive glycosides of Foxglove leaf?
A)
Murexide B)Liebermann- Burchard C)EP D)2,4-dinitro-phenylhydrazine E)Keller-Kiliani
25.
Which of the following compounds makes model for the synthesis of
methyl-psoralens?
A)
chinine B) ephedrine C) tubocurarin D) xanthotoxin E) cocaine
26.
How to take a sample of plant drug material according to the prescription of pharmacopoeia?
A)
1000g of drug is taken off the upper part of the container.
B)
100 or 200g drug has to be taken the side of the container.
C)
The number of sample depends on the number of container (N) or square root of N
(at higher N). The samples has to be taken from different parts of container
and the amount of the sample
must be sufficient for the further
analysis.
D)
Depends on the number of the container and volume of the sample.
E)
The amount and number of the sample are determined on the basis of the water content
of the
drug.
27.
Choose the right shape for the maize starch.
A)
oval B) rounded C) pentagon with a “V”
form fission in the middle of the grain
D)
triangular E)
dumb-bell shaped
28.
Why can’t
use for medical purpose Rheum raponticum instead of Rheum palmatum?
A)
Because the emodin content of Rheum raponticum is too much.
B)
Because the rhein content of the Rheum raponticum is too low.
C)
Because the chrysophanol content of Rheum palmatum is higher than in case of
Rheum raponticum.
D)
Because the Rheum raponticum contains a stilben derivative which has
undesirable
hormon activity.
E)
Because the R. raponticum has gallic acid and the amount of other tannins are
too low.
29.
Which of the following compounds transforms to chamazulen on Waterdamp distillation?
A)
lavandulol B) farnezol C) matricine D) gossypol E) parthenolid
30.
Which compound makes model for the synthesis of petidin?
A)
psoralen B) cocaine C) hyoscyamine D) morphin E) physostigmine
31.
Which of the following drug(s) contain(s) citric acid in a large amount?
A)
Bearberry leaf B)
Elder flower C)
Herniariae herba
D)
Tamarindi fructus E) Violae
odoratae radix
32.
How to get fixed oil for medical purpose?
A)
by extraction with a cold organic solvent B) by warm expression
C)
by extraction with cold water D) by cold expression E) by cooking with water
33.
The cake of ricinus seed left after expression is unfit for use as a cattle
food since it
contains
an extremely poisonous toxin known as ............................ .
A)
ricinin B) ricine C) taxol D) sinigrine E) lotaustralin
34.
Which of the following alkaloids derived from lysine?
A)
emetin B) chelidonin C) cinchonidin D) brucin E) lobelin
35.
Which of the following drugs contains inulin?
A)
Cichoriae radix B) Comfrey root C) Plantain shoot D) Foenigraeci semen E) Tanaceti herba
36.
Hasis (hashish) consists ........ of Cannabis sativa.
A)
gum of the male flowers B) resin of the
female flowers
C)
gum of the male and female flowers
D) pressed juice of the leaves
E) latex of the tops
37.
What is Opium?
A)
Latex exudate of the unriped incised capsules after air dried.
B)
Dried wateric extract of the riped capsules. C) Dried alcoholic extract of the
unriped capsules.
D)
Concentrated alcoholic extract of the poppy straw. E) Wateric extract of the riped
seeds.
38.
The common base skeleton of physiologically active ergoline alkaloids is:
A)
isolysergic acid. B) clavorubine. C)
lysergic acid. D) 2-phenylbenzopyrane. E)
elimoclavine.
39.
Codeine is:
A)
monomethyl ether of morphine. B) amide
of apomorphine. C) acetyl derivative of
morphine.
D)
dimethyl ether of papaverine. E)
diethyl ether of morphine.
40.
Skeleton of the B-type procyanidines is:
A)
flavan-3-ol. B) flavan-4-on. C) lignan. D) flavanolignan. E) flavanonol.
41.
Select the method prescribed for quantitative determination of anthraglycosides
in Pharmacopoeia Hungarica Editio VII.:
A)
gravimetry. B) high pressure
liquid chromatography. C)
spectrophotometry.
D)
gaschromatography. E)
titrimetry.
42.
Select the compound prescribed for quantitative determination on the base of
complex
formation
in Pharmacopoeia Hungarica Editio VII.:
A)
bitter substance. B) flavonoid. C) alkaloid. D) saponin. E) phenolglycoside.
43.
Which of the following physico-chemical characteristics is correct for
mucilages?
A)
foaming B) specific colour C) specific gravity D) viscosity
E) refractive index
44.
Poppy straw is the industrial raw material of morphine production because …......
A)
poppy straw contains only morphine B)
poppy straw does not contain other alkaloids
C)
poppy straw has the maximum morphine content
D)
poppy straw is the chiepest available raw material
E)
poppy straw contains morphine derivative
45.
Definition of vegetable drugs in the Pharmacopoeia:
A)
plant part used in medicine.
B)
plant part containing the highest content of the bioactive/characteristic
compound/s.
C)
dried part of the medicinal plant.
D)
plant part or its preparations described in the paragraphs of the
Pharmacopoeia.
E)
dried plant part used in medicine.
46.
The whole in toto vegetable drugs of mild activity have to be rejected when ...
A
it contains any toxic foreign matter (plant parts).
B)
it contains foreign matter (plant parts) more than prescribed in the corresponding
paragraph of the pharmacopoeia.
C)
it contains any toxic foreign matter (plant parts) which can not be separated.
D)
it contains any foreign matter (plant parts).
E)
it contains other parts of the plant more than prescribed in the corresponding
paragraph of the pharmacopoeia.
47.
A vegetable drug is considered as one of pharmacopoeial quality, when:
A)
it meets both the general requirements of the pharmacopoeia and the
requirements
of the corresponding paragraph in the
pharmacopoeia.
B)
it meets the requirements of the corresponding paragraph in the pharmacopoeia.
C)
it meets the requirements of the national Standard I.
D)
it meets the general requirements of the pharmacopoeia.
E)
it meets both the general requirements of the pharmacopoeia and the
requirements
of the national Standard I.
48.
Which of the following statement is associated with the name of Janos KABAY?
A)
Isolation of morphine. B) Structure
elucidation of morphine.
C)
Industrial production of morphinanes from poppy straw.
D)
Industrial production of morphinanes from opium.
E)
Industrial production of morphinanes from unriped poppy capsules.
49.
Which of the following statement is associated with the name of Miklos BEKESSY?
A)
Industrial production of essential oils by steam distillation.
B)
Industrial production of poppy alkaloids. C) Cultivation of ergot.
D) Isolation of morphine. E) Production of
ergot alkaloids by fermentation.
50.
Whose name of the followings is associated with the discovery of morphine?
A)
Caventou B) Serturner C) Stoll D) Pelletier E) Scheele
51.
Select the method used for the fixed vegetable oil-preparation of
pharmacopoeial quality:
A)
solvent extraction.
B) expression. C)
cold-expression.
D)
steam distillation.
E) expression and solvent extraction.
52.
Quality control of medicinal plants is carried out by authority in Hungary:
A)
National Pharmaceutical Institute. B) any
institute for quality control.
C)
Herbaria (National Medicinal Plant Trading Company).
D)
Hungarian Bureau of Standards. E) Research Institute for Medicinal
Plants.
53.
Which of the following vegetable drugs has the highest caffeine content?
A)
Mate folium B) Theae folium C) Guarana D) Coffeae semen E) Colae semen
54.
Which of the following cannabinoids is narcotic?
A)
cannabichromene B) tetrahydrocannabinol C) cannabigerol D) cannabinol
E) cannabidiol
55.
Select the vegetable drug which has the highest alkaloid content!
A)
Chinae succirubrae cortex
B) Stramonii folium C) Ipecacuanhae radix
D)
Strychni semen E)
Belladonnae radix
56.
Which of the following constituents is not present in Aetheroleum chamomillae?
A)
chamazulene B) matricin C) spatulenol D) α-Bisabolol E) en-in-dicycloethers
57.
Which of the following constituents is not present in Chamomillae anthodium?
A)
chamazulene B) matricin C) spatulenol D) α-Bisabolol E) en-in-dicycloethers
58.
Which of the followings is true for inulin?
A)
arabin B) pectin C) galaktane D) mannan E) fructosane
59.
Number of vegetable drugs which are not subject to restriction in Hungary?
A)
less than 50
B) between 50 and 100
C) between 100 and 300
D)
between 300 and 500 E)
more than 500
60.
Which of the followings is correct for the molecular mass of tannins?
A)
less than 200
B) between 200 and 500
C) between 500 and 1000
D)
between 1000 and 3000 E)
more than 3000
61.
Which of the following vegetable drugs is carminative?
A)
Frangulae cortex B)
Centaurii herba C) Silybi
mariani fructus
D)
Foeniculi fructus E)
Graminis rhizoma
62.
Which of the following vegetable drugs contains ajoene?
A)
Valerianae radix B)
Agrimoniae herba C)
Echinaceae radix
D)
Ginseng radix E) Allii
sativi bulbus
63.
Which of the following plant constituents can be characterized by reversible
complexation
with proteins?
A)
alkaloids
B) saponins
C) tannins
D)
mucilages E) anthraglycosides
64.
Morphine content in Opium is:
A)
less than 0.5 %. B)
between 0.5 and 1.0 %. C)
between 1.0 and 5 %.
D)
between 5 and 10 %. E)
between 10 and 15 %.
65.
Which of the following vegetable drugs contains aucubin?
A)
Marrubii herba B)
Agrimoniae herba C)
Valerianae rhizoma and radix
D)
Plantaginis folium E)
Cyani flos
66.
Which of the following vegetable drugs is in the category of amara aromatica?
A)
Absinthii herba
B) Cardui benedicti herba
C) Gentianae radix
D)
Trifolii fibrini folium
E) Centaurii herba
67.
Hide powder is used in the traditional method of tannin quantitation because
...
A)
hide powder gives a colour reaction with tannin. B) hide powder reacts with polyphenols.
C)
hide powder reduces tannins. D) hide
powder oxidizes polyphenols.
E)
hide powder reacts with tannins.
68.
What type of compound is arbutin used in urological infections?
A)
flavonoid glycoside
B) phenolic glycoside C) furanocoumarin
D)
iridoid glycoside
E) gallotannin
69.
How can you extract tertiary alkaloids in the form of salts?
A)
Extracting with organic solvent like chloroform.
B)
Boiling with aqueous ammonia.
C)
Extracting with organic solvent containing alkaline solution.
D)
Extracting with organic solvent containing acidic solution.
E)
Extracting with an acidic aqueous solution.
70.
Ginseng saponins are of the ............... series
A)
lupine B) ursane C) abietane D) oleanane E) dammarane
71.
Choose the right compound for the following structure:
A)
podophyllotoxin B) taxifolin C) silybin D) hyperoside E) silychrystine
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