Choose
the correct answers.
Q.1 Repeated administration of tyramine
results in its decreasing effectiveness:
a) Gets detoxicated easily b) Displaces nor-adrenaline from
nerve endings binding site
c) Displaces adrenaline from nerve endings
binding site d) None of
these
Q.2 Atropine on hydrolysis with barium
hydrochloride gives:
a) Tropanol and tropic acid b) Scopine and tropic
acid
c) Ecgonine and benzoic acid d) Benzyl ecgonine and
methanol
Q.3 The concentration of sucrose in simple
syrup B.P. is
a) 85 % b) 60.70 % c) 66.70 % d) 40.74 %
Q.4 Stratified cork forked fibres are the
characteristic diagnostic features of:
a) Apocynaceae b) Scrophulariaceae c) Gnetaceae d) Polygonaceae
Q.5 most accepted mechanism for developing
bacterial resistance to sulphonamides
a) An increasing capacity to inactivate or
destroy the drug
b) An alternative metabolic pathway for
synthesis of an essential metabolite
c) An
increased product of drug antagonist d) An alteration in enzyme that
utilize PABA
Q.6 C17 α-β unsaturated lactone ring is a
common feature in:
a) Digitalis and squill glycosides b) Digitalis and strophanthus
glycosides
c) Digitalis and Senna glycosides d) Digitalis and amygdalin
Q.7 For drying blood plasma the following
technique is used:
a) Spray drying b) Freeze drying c) Vacuum drying d) Fluid bed drying
Q.8 C3 O-glycoside digitoxin is used for:
a) Cardiac action b)
Hypotensive action
c) Precipitating steroids from solution d) precipitating anthraquinone
glycosides
Q.9 Chemical name of amoxicillin is
a) 6-[D-(-) α-amino –p-hydroxy phenyl
acetamide] penicillinic acid
b) 4-[D-(-) α- amino –p-hydroxy phenyl
acetamide] penicillinic acid
c) β-hydroxyl analogue of benzyl penicillin d) α-carboxy benzyl
penicillin
Q.10 The HLB value of sodium lauryl sulphate
is:
a) 6.5 b) 13.5 c) 25 d) 40.0
Q.11 Claviceps purpurea yields after
infecting ovaries of Graminaceous plants:
a) Digitoxin b) Lysergic acid derivatives c) Reserpine d) Polypeptides
Q.12 In the official bioassay of Erythromycin
the strain used is
a) Bacillus subtilis b) Micrococcus luteus c) Salmonella typhi d) Escherichia coli
Q.13 The disintegration time for sugar coated
tablet is
a) 30 minutes b) 45 minutes c) 60 minutes d) 75 minutes
Q.14 Idioblast of crystal layer of calcium
oxalate is a diagnostic feature of:
a) Hyoscyamous niger leaves b) Deadly night shade leaves c) Cinchona bark d) Senna leaves
Q.15 Antibiotic which interacts with calcium
ion is:
a) Erythromycin b) Streptomycin c) Tetracycline d) Ampicillin
Q.16 flow rate of granules from the hopper
can be improved by adding:
a) Disintetrant b)
Glidant c) Binder d) lubricant
Q.17 Silicon carbide rod heated to high
temperature is used as a
a) Detector in infra red spectroscopy b) Source of light in infra red
spectroscopy
c) Source of light fluorimetry d) Detector in gas
chromatography
Q.18 Anomocytic stomata are found in the
leaves of:
a) Fox glove b) Urginea maritime c) Cassia acutifolia d) Atropa belladonna
Q.19 Liver microsomal enzymes are stimulated
(enzyme induction) by:
a) Cimetidine b) Phenobarbitone c) Procaine d) Adrenaline
Q.20 Enteric coating is achieved by using:
a) Hydroxy propyl methyl cellulose b) Carboxy methyl cellulose
c) Cellulose acetate phthalate d) Povidone
Q.21Carr Price reaction is applied for the
photometric evaluation of:
a) Vitamin A b) Tocopherol c) Nandrolone phenyl propionate d) Benzodiazepine
Q.22 Peroxidase enzyme present in acacia is
identified by:
a) Borntrager’s test b) Molish’s test c) Oxidation and excretion in
benzene
d) oxidation and treatment with benzidine
Q.23 Prostaglandins are a group of related
a) Alcohol b) Aldehyde c) Fatty acid d) Alkaloids
Q.24 License to sell drugs specified in
Schedule C and C1 is given in form number:
a) 19 b) 18 c) 21 d) 24
Q.25 Liquid paraffin exhibits:
a) Plastic flow b) Newtonian flow c) Pseudo plastic flow d) Dilatant flow
Q.26 Estrogenic and progestrogenic
combination mainly:
a) Inhibits the ovulation b) Inhibits the
implantation of the fertilized ovum
c) Inhibits the fertilization of ovum d) Inhibits development of endometrium
Q.27 More of earthy matter in a rhizome is
determined by:
a) Total ash value b) The earthy material is separated and then
weighted
c) The rhizome is washed in water and then in
hydrochloric acid finally it is weighed
d) Acid insoluble ash value
Q.28 Lidocaine is synthesized from:
a) 2, 6-dimethyl-5-amino methyl benzene b) 2, 6-dimethyl-5-nitro methyl benzene
c) 2, 6-xylidine d)
2-methyl-6-ethyl-5-amino methyl benzene
Q.29 Sterilization temperature for aqueous
solution in autoclave (moist heat) is:
a) 720C b) 1210C c) 1470C d) 1600C
Q.30 Following combination is suggested in the
treatment of Leprosy:
a) Dapsone + Ampicillin + Clofazimine b) Dapsone + Clofazimine + Rifampin
c) Dapsone + Erythromycin + Rifampin d) Dapsone + Tetracycline +
Streptomycin
Q.31 The gummy nature of Astragalus gummifier
is dependent on:
a) More of methoxyl groups of Bassorin b) The carbohydrate content
c) More of hydroxyl groups of the sugar
moiety d) More of protein content
of the drug
Q.32 The vitamin administered with Isoniazid
to minimize its adverse reaction is:
a) Vitamin A b) Pyridoxine c) Biotin d) Pantothenic acid
Q.33 For the synthesis of nitrofurantoin
which one of the following of chemicals are used
a) 5-nitro-2-furadehyde and 1-amino hydantoin
b) 5-nitro-2-furadehyde and hydantoin
c)
5-amino-2-furadehyde 2-amino hydantoin
d) 5-amino-2-furadehyde & Barbituric acid
Q.34 To get the optimum optical density of
the solution for 1 cm thick layer the concentration
should be about:
a) 10-4 mole/lit b) 10-7 mole/lit c) 0.1 gm/lit d) 0.5 gm/lit
Q.35 The sugar moiety of Digitalis purpurea
is:
a) 2, 6-deoxy allose b) 2, 6-deoxy glucose c) 2-deoxy Rhamanose d) 2, 6-deoxy galactose
Q.36 Addition of sodium chloride to sodium
oleate emulsion will:
a) Stabilize emulsion b) Destabilize emulsion
c) Decrease the globule size of the emulsion d) none of these
Q.37 Anti-hypertensive drug which inhibits
the renin Angiotensin system is:
a) Reserpine b) Captopril c) Methyldopa d) Propranolol
Q.38 Acidity of ascorbic acid is due to
presence of:
a) Free carboxylic group b) A number of hydroxyl groups c) Enolic group d) none
Q.39 Progesterone injection BP is sterile
solution in:
a) Water b) Ethyl acetate c) Propylene glycol Glycerol d) none of these
Q.40 Thiamine on treatment with sodium
sulfite solution and sulfur dioxide yields:
a) Pyrimidine and thiazole derivatives b) pyridine and
thiazole derivatives
c) 2, 3, 4-trihydropyridine and thiophene
derivatives d) pyrimidine and thiophene der.
(2) Q.1 Identify the correct Skelton ring
present in the following compounds from the ring systems listed a to e.
2.i.1 Riboflavin a) Per hydro
cyclopentanophenanthrene
2.i.2 Estrone b) 1, 8-Naphthyridine
2.i.3 Indomethacin c) Indole
2.i.4 Naldixic acid d) Quinoline
e) Iso alloxazine
Q.2 Choose the instrument or apparatus listed
from a to e to study the following:
2.ii.1 Rheology of semi solids a) Andreasen Pipette
2.ii.2 Hardness of tablets b) Monsanto tester
2.ii.3 Particle size in suspension c) Ultrasonifier
2.ii.4 Homogenization of emulsion d) Viscometer
e) Zeta meter
Q.3 Given below are some Microscopical
diagnostic features of the drugs listed a to e.
Choose the appropriate one
2.iii.1 Unlignified seplate fibre a)
Rhubarb
2.iii.2 Raphides of calcium oxalate embedded
in mucilage b) Liquorice
2.iii.3 Anisocytic type of stomata
c) Ginger
2.iii.4 Star spots d)
Squill
e) Solanaceous
plant
Q.4 Choose the most appropriate drug for the
following:
2.iv.1 Potassium sparing diuretic a) Spironolactone
2.iv.2 Loop diuretic
b) Mannitol
2.iv.3 Osmotic diuretic c)
Furosemide
2.iv.4 Carbonic anhydrase inhibitor d) Acetazolamide
e) Aldosterone
Q.5 Transmitted color that corresponds to
various wavelength range as listed under a to e.
Choose the correct wavelength for the color.
2.v.1 Green a) 435 – 480 nm
2.v.2 Orange b) 500 – 560 nm
2.v.3 Yellow c) 580 – 595 nm
2.v.4 Red d) 595 – 650
nm
e) 650 – 780 nm
Q.6 Given below are equipment used in the
manufacture of the following products a to e.
2.vi.1 Zanasi a) Tablet granules
2.vi.2 HEPA filter b) Tablet coating
2.vi.3 Chilsonator c) Emulsion
2.vi.4 Accelacota d) Injectable
e)
Capsules
Q.7 Match the following with the Schedules
listed a to e correctly.
2.vii.1 Requirements of factory premises a)
P
2.vii.2 Standards for disinfectant fluids b) V
2.vii.3 Life period of drugs c)
N
2.vii.4 List of minimum equipments for the
efficient running of pharmacy d) O
e)
M
Q.8 Following are the reactions/tests
observed in case of drugs listed in a to d.
2.viii.1When fixed oil is exposed to UV rays,
blue fluorescence is produced a)
Digoxin
2.viii.2 On oxidation with KMnO4,
benzaldehyde odour is perceived b) Benzoin
2.viii.3 With ammonical Quaxon characteristic
ballooned fibre is seen under microscope
c)
Cinchona
2.viii.4 Bark powder exhibits fluorescence
with sulphuric acid d) Palmodin
e)
Gossypium barbadance
Q.9 Mechanism of Anti-tubercular action of
the drugs listed are indicated in a to e.
2.ix.1 Ethambutol a) Prevents the synthesis
of protein and DNA and reduces
RNA
synthesis
2.ix.2 P.A.S. b) Interfere with several steps in protein
synthesis
2.ix.3 Cycloserine c) Competitive inhibition
2.ix.4 Ethionamide d) Inhibits peptide synthesis in Mycobacteria
e) Inhibits DNA directed RNA synthesis
Q.10 Given below are the receptors and their
antagonist (a to e). Match them correctly.
2.x.1 Histaminic H2 receptor a) Atropine
2.x.2 Muscarinic receptor b) Ranitidine
2.x.3 Adrenaline α-receptor c) Pentolamine
2.x.4 Adrenaline β-receptor d) Metaraminol
e) Metoprolol
Q.11 Match the following regions in GIT with the
pH level indicated from a to e
2.xi.1 Mouth a) 5.0 – 6.0
2.xi.2 Stomach b) 6.8 – 7.5
2.xi.3 Duodenum c) 6.8 – 7.0
2.xi.4 Large Intestine d) 3.0 – 5.0
e) 1.5
– 3.0
Q.12 Listed a to e are some of the analytical
constants. Match them correctly with the
drugs given below.
2.xii.1 A leafy drug a) total ash value
2.xii.2 A bark b) Cineole content
2.xii.3 Eucalyptus oil c) Fibre length
2.xii.4 A fixed oil having more of
unsaturated fatty acid glyceride d) Iodine value
e) Stomatal index
Q.13 Match the ingredients listed a to e with
the purpose for which they are used in the formulations:
2.xiii.1 Film coating a) Sodium benzoate
2.xiii.2 Syrups b) Ethyl
cellulose
2.xiii.3 Emulsification c) Eudragit
2.xiii.4 Enteric coating d) Sucrose
e) Sodium oleate
Q.14 Match the biological activity listed
under a to e for the following compounds
2.xiv.1 1, 3-propanediol-2-methyl-2-propyl
carbamate a)
Antimalarial
2.xiv.2 2-chloro-10-[3-(dimethylamino)propyl]
phenothiazine b) Bactericidal->
-> to anaerobic and microphilic organism
2.xiv.3 5-Nitro-2-furaldehyde-semicarbazone c) Antibacterial
2.xiv.4 2-methyl-5-nitro Imidazole-1-ethanol d) Relief of anxiety and tension
e) Tranquilizer
Q.15 Given below are the drugs a to e and the
ailments for which they recommended.
2.xv.1 Parkinsonism a) Methyl dopa
2.xv.2 Hypertension b) Levodopa with decarboxylase inhibitor
2.xv.3 Nasal decongestion c) Neostigmine
2.xv.4 Myasthenia gravis d) Phenyl
propanolamine
e) Ibuprofen
Q.16 Given below are some of the drugs and
their mode of action (a to e) .
2.xvi.1 Hydralazine a) Vasodilator by direct
action
2.xvi.2 Phenothiazine b) Inhibits the vaso
constrictor and pressor effect of 5 HT
2.xvi.3 Methysergide c) Antagonist to H1
receptor Histamine
2.xvi.4 Tolazamide d) Stimulate the islet
tissue to secret insulin
e) Inhibiting the enzyme carbonic anhydrase
Q.17 Given below in a to e are the list of
drug appropriate tests are given below for the drugs.
2.xvii.1 Alcoholic solution of α-naphthol and
sulphuric acid a) Atropine
2.xvii.2 Murexide test b) Reserpine
2.xvii.3 Para dimethyl benzaldehyde c)
Caffeine
2.xvii.4 Ninhydrin d)
Gelatin
e)
Triticum sativum powder
Q.18 Given below in a to e are the names of
instruments used for the determination of the
following parameters. Match them correctly.
2.xviii.1 Particle volume a) Clarity
apparatus
2.xviii.2 Presence of Foreign particle b) Du Nouy ring
2.xviii.3 Surface tension c) Coulter
counter
2.xviii.4 Presence of polymorphism d) Compactor
e) Differential thermal calorimeter
Q.19 Choose the correct starting material
listed a to e for the synthesis of the following drugs
2.xix.1 Cortisone a) Diasogenin
2.xix.2 Progesterone b) β-ionone
2.xix.3 Testosterone c) Spirostanol
2.xix.4 Vitamin A d) Sarmentogenin
e) anthracin
Q.20 Given below the types of ointments
bases. Match them with the correct ointments in a to e.
2.xx.1 Absorption base a) Emulsifying ointment
2.xx.2 Oilogenous base b) Hydrophilic ointment
2.xx.3 Emulsion base c) Oily cream
2.xx.4 Water soluble base d) Kaolin poultice
e) Simple ointment
Answer
Key-1989 (Multiple Choice)
1.b 2.a 3.c 4.a 5.d 6.b 7.b 8.a 9.a 10.d 11.b
12.b 13.c 14.c 15.c 16.b 17.b 18.a 19.b 20.c 21.a 22.d 23.c 24.c 25.c 26.a 27.c
28.c 29.b 30.b 31.a 32.b 33.a 34.b 35.b 36.b 37.b 38.c 39.c 40.a
Match
the column
1. (1) e (2) a (3) c (4) b 2. (1) d (2) b (3) a (4) c
3. (1) c (2) d (3) e (4) a 4.
(1) a (2) c (3) b (4) d
5. (1) b (2) d (3) c (4) e 6. (1)
e (2) d (3) a (4) b
7. (1) e (2) d (3) a (4) c 8.
(1) d (2) b (3) e (4) c
9. (1) d (2) c (3) a (4) b 10. (1) b (2) a (3) c (4) e
11. (1) c (2) d (3) a (4) b 12. (1) e (2) c (3) b (4) d
13. (1) b (2) d (3) e (4) c 14. (1) d (2) e (3) c (4) b
15. (1) b (2) a (3) d (4) c 16. (1) a (2) c (3) b (4) d
17. (1) e (2) c (3) b (4) d 18. (1) c (2) a (3) b (4) e
19. (1) c (2) a (3) d (4) b 20. (1) d (2) e (3) c (4) b
No comments:
Post a Comment