VPTAC Pharma Quiz-28 (MCQ)

1. The most abundant free nucleotide in mammalian cells is

A. ATP            B. GTP                  C. FAD                  D. NAD

2. Potassium content of muscle tissue in mg/100 ml is about

A. 50-100         B. 100-150              C. 150-200           D. 250-400   

3. A synthetic  form of vitamin K is

A. Menadione      B. Farnoquinone     C. Phylloquinone    D. None of the above

4. Active uptake of glucose is decreased in

A. Ouabain         B.  Digoxin        C. Phlorrizin              D. Alloxan

Phlorizin is a 2'-glucoside of phloretin. It belongs to the group of dihydrochalcones, a type of flavonoids.Phlorizin is a competitive inhibitor of SGLT1 and SGLT2 because it competes with D-glucose for binding to the carrier; this reduces renal glucose transport, lowering the amount of glucose in the blood

5. Chylomicron remnants are catabolised in

A. Intestine         B. Liver             C. Liver and intestine             D. Adipose tissue

Chylomicrons (from the Greek chylo, meaning juice or milky fluid, and micron, meaning small particle) are lipoprotein particles that consist of triglycerides (85-92%), phospholipids (6-12%), cholesterol (1-3%), and proteins (1-2%). They transport dietary lipids from the intestines to other locations in the body. Chylomicrons are one of the five major groups of lipoproteins (chylomicrons, VLDL, IDL, LDL, HDL) that enable fats and cholesterol to move within the water-based solution of the bloodstream.

6. Co-lipase is a

A. Bile salt         B. Protein          C. Vitamin              D. Phospholipid

Colipase is a protein co-enzyme required for optimal enzyme activity of pancreatic lipase. It is secreted by the pancreas in an inactive form, procolipase, which is activated in the intestinal lumen by trypsin. Its function is to prevent the inhibitory effect of bile salts on the lipase-catalyzed intraduodenal hydrolysis of dietary long-chain triglycerides.

7. Free ammonia is liberated during the catabolism of

A. Cytosine               B. Uracil                C. Thymine               D. All of above

8. In males luteinising hormone acts on

A. Leyding cells     B. Prostage gland           C. Sertoli cells          D. All of above

9. For an idea suspension, the sedimentation volume should be:

A. Equal to one        B. Less than one          C. More than one           D. Zero

10. Which compound is a natural emulsifying  agent?

A. Acacia         B. Polysorbate 20           C. Lactose              D. Polysorbate 80

1.A    2.C    3.A    4.C    5.B    6.B    7.D    8.D    9.A    10.A